Li-Fraumeni Syndrome (LFS)
Li-Fraumeni Syndrome (LFS) is linked to a mutation in the TP53 tumor suppressor gene. There are many types of TP53 mutations. People with this mutation have a higher risk of developing cancer over their lifetime. LFS affects each individual differently, even within the same family. Some families with LFS have higher rates of cancer incidence, while others do not.
Living LFS is active and public on social media. We welcome you to become a part of any of our public online communities that suit your preferences.
We have separate private Facebook groups specifically for those living with LFS and for those who supporting someone living with LFS.
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We encourage, empower, and educate those living with Li-Fraumeni Syndrome by connecting them with care, resources, and others who are Living LFS.
Latest Blog Posts

Sex After Cancer: Survivorship and Intimacy
After treatment for cancer, it’s not uncommon to experience vaginal dryness or vaginal atrophy, incontinence, menopause symptoms, and significant hormonal and emotional changes. With a

What is Breast MRI Like?
– by Andi Last Take off my clothes, put on the hospital gown, get a needle in my arm, the nurse misses the vein, try

Help Us Fill the Gap Left by Amazon Smile
$3,947.58. That’s how much money went into the Li-Fraumeni syndrome (LFS) community, thanks to everyone who chose Living LFS as their Amazon Smile charity. We